7-[2-Hydroxy(propyl-d6)]guanine

7-[2-Hydroxy(propyl-d6)]guanine - Names and Identifiers

Name	7-[2-Hydroxy(propyl-d6)]guanine
Synonyms	7-[2-Hydroxy(propyl-d6)]guanine N7-[2-Hydroxy(propyl-d6)]guanine [2H6]-7- (2-Hydroxypropyl)guanine 2-AMino-1,7-dihydro-7-[2-hydroxy(propyl-d6)]-6H-purin-6-one
CAS	1346599-30-1

7-[2-Hydroxy(propyl-d6)]guanine - Physico-chemical Properties

Molecular Formula	C8H11N5O2
Molar Mass	209.20524
Melting Point	>300°C (dec.)
Solubility	DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
Appearance	Solid
Color	Off-White to Pale Beige
Storage Condition	-20°C Freezer

7-[2-Hydroxy(propyl-d6)]guanine - Introduction

7-[2-Hydroxy(propyl-d6)]guanine (7-[2-Hydroxy(propyl-d6)]guanine) is a chemical substance with the following properties:

Nature:
-chemical formula: C12H12D6N5O2
-Molecular weight: 266.31g/mol
-Appearance: White crystalline solid
-Melting point: 240-245 ° C
-Solubility: insoluble in water, soluble in non-polar solvents such as chloroform, dichloromethane, etc.

Use:
- 7-[2-Hydroxy(propyl-d6)]guanine is mainly used as an isotope labeling reagent in nuclear magnetic resonance (NMR) experiments.
-It is usually used to mark specific locations of DNA or RNA to track and study the structure, synthesis and metabolism of these biological molecules.

Preparation Method:
The preparation method of -7-[2-Hydroxy(propyl-d6)]guanine can be achieved by chemical synthesis. The specific steps include: firstly reacting guanine with 2-hydroxypropanol, and then performing the same reaction with deuterated 2-hydroxypropanol to finally obtain the target product.

Safety Information:
- 7-[2-Hydroxy(propyl-d6)] safety information related to guanine is currently less reported. General laboratory safety practices should be followed in the handling and use of the substance, and direct contact with trauma or ingestion should be avoided. In case of discomfort or accident, seek medical attention and bring material-related safety data.

Last Update：2024-04-10 22:29:15